Gold Nano-Urchins Enhanced Surface Plasmon Resonance (SPR) BIOSENSORS for the Detection of Estrogen Receptor Alpha (ERα)

Breast cancer is the deadliest form of in women, but it also has very high survival rates when treated early. Existing breast detection methods such as mammography are ineffective early due to low uptake among women and need for regular screening. Therefore, biosensors have been proposed an alternative method cost-effective screening which may encourage more go regularly. In this paper, a gold nano-urchins enhanced plasmonic sensor demonstrated typical marker, estrogen receptor alpha (ERα). The localized field confinement effect sharp features amplifies biosensing signal improves its sensitivity compared conventional surface plasmon resonance (SPR) biosensor.